Point of care devices like glucose monitors have become omnipresent in everyday life, yet diseases like kidney disease can go unnoticed. At SAL, we aim to design unobtrusive wearable systems that can detect kidney disease specific biomarkers (Cystatin-C, Creatinine, & Urea) in sweat that have high sensitivity and can be fabricated with scalable technologies like printing. To ensure minimal interferences from skin and potential contaminants and reduce false readings, a microfluidic sweat generation module is required to deliver sweat to the sensors. The goal of this thesis is the development of a printed microfluidic system for sweat generation & collection. The following activities will be part of this thesis:

• Perform literature review (scientific articles, patents, etc.)
• Optimize microfluidics fabrication via printing methodologies (screen printing, inkjet printing, roll to roll imprinting)
• Characterize mechanical properties, flow efficiencies, and adsorption characteristics of microfluidics materials. 
• Provide recommendations to minimize adsorption of targeted biomolecules.
• Support integration activities with printed biosensors and iontophoresis electrodes 
• Perform data analysis and prepare reports.